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KMID : 0615720080250020211
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Jouranl of Korean Acupuncture and Moxibustion society
2008 Volume.25 No. 2 p.211 ~ p.226
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The Effects of Herbal Acupuncture(Fructus Hordei Germiniatus) at Acupoint Jung-wan() on the Obese Rats Induced by High Fat Diet
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Cho Myung-Rae
Ryu Chung-Ryul
Lee Ji-Eun
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Abstract
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Objectives : This research was performed to investigate the effects of Fructus Hordei Germiniatus-herbal acupuncture(HA; herbal acupuncture) at acupoint Jung-wan(CV12) on weight gain, food consumption, food efficiency, serum of lipid concentrations and liver function of rats fed high fat diet for 7weeks.
Methods : Experimental groups were divided into high fat diet group(Control), high fat diet and saline injection at acupoint CV12 treated group(Saline), high fat diet and Fructus Hordei Germiniatus-HA at acupoint CV12treated groups. According to HA concentration, HA groups were classified into 4 groups ; HA-1(0.108 mg/g/ml), HA-2(0.054 mg/g/ml), HA-3(0.022 mg/g/ml), HA-4(0.011 mg/g/ml). HA was treated at 20㎕ per 4days, total 12times in 49days.
Results : 1. Body weight per week was significantly decreased in HA-1, HA-2, HA-3 and HA-4 And body weight per day was significantly decreased in HA-3. 2. Food consumption per week was significantly decreased in HA-1, HA-2, HA-3 and HA-4. 3. Food efficiency per week was significantly decreased in HA-2, HA-3 and HA-4 And food efficiency per day was significantly decreased in HA-3. 4. The level of serum total cholesterol was significantly decreased in HA-1 and HA-3 And the level of serum HDL-cholesterol was significantly decreased in HA-1. 5. The level of serum triglyceride was significantly decreased in HA-1, HA-2, HA-3 and HA-4. And the level of serum total bilirubin was significantly decreased in HA-1and HA-2. 6. The level of serum AST was significantly decreased in HA-2 and HA-3 And the level of serum ALT, r-GTP were significantly decreased in HA-2.
Conclusions : According to the above results, Fructus Hordei Germiniatus-HA at acupoint CV12 can control body weight, food consumption, food efficiency, serum lipid concentrations and liver function. Asthe same time this kind of Fructus Hordei Germiniatus-HA does not seem to be injurious on liver function. To use Fructus Hordei Germiniatus-HA for obesity, further studies about their underlying mechanism may be needed.
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KEYWORD
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Jung-wan, Herbal Acupuncture, Fructus Hordei Germiniatus, obesity
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